Cerebrospinal fluid lipoprotein-mediated cholesterol delivery to neurons is impaired in Alzheimer's disease and involves APOE4

In the central nervous system, apolipoprotein (APO)E-containing lipoprotein particles mediate the transport of glial-derived cholesterol to neurons, which is essential for neuronal membrane remodeling and maintenance of the myelin sheath. We aimed to examine cholesterol transport via lipoprotein par...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Journal of Lipid Research
المؤلفون الرئيسيون:	Carla Borràs, Marina Canyelles, David Santos, Noemí Rotllan, Estefanía Núñez, Jesús Vázquez, Daniel Maspoch, Mary Cano-Sarabia, Qi Zhao, Maria Carmona-Iragui, Sònia Sirisi, Alberto Lleó, Juan Fortea, Daniel Alcolea, Francisco Blanco-Vaca, Joan Carles Escolà-Gil, Mireia Tondo
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2025-08-01
الموضوعات:	Alzheimer's disease APOE cholesterol CSF lipoprotein
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S0022227525001270