The difference in CD4+ T cell immunity between high- and low-virulence Tembusu viruses is mainly related to residues 151 and 304 in the envelope protein

Tembusu virus (TMUV) can result in a severe disease affecting domestic ducks. The role of T cells in protection from TMUV infection and the molecular basis of T cell-mediated protection against TMUV remain largely uncharacterized. Here, we used the high-virulence TMUV strain Y and the low-virulence...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Runze Meng, Baolin Yang, Chonglun Feng, Jingjing Huang, Xiaoyan Wang, Dabing Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Subjects:	Tembusu virus virulence cellular immune response CD4+ T cell immunity CD8+ T cell immunity
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.890263/full