Pigs lacking the SRCR5 domain of CD163 protein demonstrate heritable resistance to the PRRS virus and no changes in animal performance from birth to maturity

Porcine reproductive and respiratory syndrome (PRRS) is one of the world’s most persistent viral pig diseases, with a significant economic impact on the pig industry. PRRS affects pigs of all ages, causing late-term abortions and stillbirths in sows, respiratory disease in piglets, and increased sus...

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Bibliographic Details

Published in:	Frontiers in Genome Editing
Main Authors:	Clint Nesbitt, Lucina Galina Pantoja, Benjamin Beaton, Ching-Yi Chen, Matt Culbertson, Perry Harms, Justin Holl, Andrzej Sosnicki, Srinu Reddy, Marisa Rotolo, Elena Rice
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Subjects:	pigs porcine PRRS gene editing CRISPR disease resistance
Online Access:	https://www.frontiersin.org/articles/10.3389/fgeed.2024.1322012/full