Physical Interaction between Cyclin-Dependent Kinase 5 (CDK5) and Clock Factors Affects the Circadian Rhythmicity in Peripheral Oscillators

Circadian rhythms are self-sustained oscillators with a period of 24 h that is based on the output of transcriptional and post-translational feedback loops. Phosphorylation is considered one of the most important post-translational modifications affecting rhythmicity from cyanobacteria to mammals. F...

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Bibliographic Details

Published in:	Clocks & Sleep
Main Authors:	Jürgen A. Ripperger, Rohit Chavan, Urs Albrecht, Andrea Brenna
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Subjects:	CDK5 circadian mouse embryonic fibroblasts phosphorylation period length
Online Access:	https://www.mdpi.com/2624-5175/4/1/17