The Role of Hippo Signaling Pathway and ILK in the Pathophysiology of Human Hypertrophic Scars and Keloids: An Immunohistochemical Investigation

Background: Keloids and hypertrophic scars are characterized by abnormal fibroblast activation and proliferation. While their molecular pathogenesis remains unclear, myofibroblasts have been associated with their development. Hippo pathway effectors YAP/TAZ promote cell proliferation and matrix stif...

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Bibliographic Details

Published in:	Cells
Main Authors:	Ilias G. Petrou, Sofia Nikou, Srinivas Madduri, Martha Nifora, Vasiliki Bravou, Daniel F. Kalbermatten
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	keloids Hippo pathway ILK hypertrophic scars wound healing scars
Online Access:	https://www.mdpi.com/2073-4409/11/21/3426