Chemotherapy-induced intestinal epithelial damage directly promotes galectin-9-driven modulation of T cell behavior

Summary: The intestine is vulnerable to chemotherapy-induced damage due to the high rate of intestinal epithelial cell (IEC) proliferation. We have developed a human intestinal organoid-based 3D model system to study the direct effect of chemotherapy-induced IEC damage on T cell behavior. Exposure o...

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Bibliographic Details
Published in:iScience
Main Authors: Suze A. Jansen, Alessandro Cutilli, Coco de Koning, Marliek van Hoesel, Cynthia L. Frederiks, Leire Saiz Sierra, Stefan Nierkens, Michal Mokry, Edward E.S. Nieuwenhuis, Alan M. Hanash, Enric Mocholi, Paul J. Coffer, Caroline A. Lindemans
Format: Article
Language:English
Published: Elsevier 2024-06-01
Subjects:
Molecular biology
Immunology
Stem cells research
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224012975

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http://www.sciencedirect.com/science/article/pii/S2589004224012975

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