Mechanism of Resistance Development in <i>E. coli</i> against TCAT, a Trimethoprim-Based Photoswitchable Antibiotic

During the last decades, a continuous rise of multi-drug resistant pathogens has threatened antibiotic efficacy. To tackle this key challenge, novel antimicrobial therapies are needed with increased specificity for the site of infection. Photopharmacology could enable such specificity by allowing fo...

詳細記述

書誌詳細

出版年:	Pharmaceuticals
主要な著者:	Anna I. Lauxen, Piermichele Kobauri, Michael Wegener, Mickel J. Hansen, Nicole S. Galenkamp, Giovanni Maglia, Wiktor Szymanski, Ben L. Feringa, Oscar P. Kuipers
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2021-04-01
主題:	photoswitchable antibiotic trimethoprim TCAT resistance mechanism <i>E. coli</i> TolC
オンライン･アクセス:	https://www.mdpi.com/1424-8247/14/5/392