Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci

To uncover novel significant association signals (p<5×10−8), genome-wide association studies (GWAS) requires increasingly larger sample sizes to overcome statistical correction for multiple testing. As an alternative, we aimed to identify associations among suggestive signals (5 × 10−8≤p&...

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Bibliographic Details

Published in:	eLife
Main Authors:	Reza K Hammond, Matthew C Pahl, Chun Su, Diana L Cousminer, Michelle E Leonard, Sumei Lu, Claudia A Doege, Yadav Wagley, Kenyaita M Hodge, Chiara Lasconi, Matthew E Johnson, James A Pippin, Kurt D Hankenson, Rudolph L Leibel, Alessandra Chesi, Andrew D Wells, Struan FA Grant
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2021-01-01
Subjects:	bioinformatics GWAS functional genomics Capture C body mass index waist-hip ratio
Online Access:	https://elifesciences.org/articles/62206