TRIM32-Cytoplasmic-Body Formation Is an ATP-Consuming Process Stimulated by HSP70 in Cells.

The spontaneous and energy-releasing reaction of protein aggregation is typically prevented by cellular quality control machinery (QC). TRIM32 is a member of the TRIM (tripartite motif-containing) ubiquitin E3 ligases, and when overexpressed in cultured cells, readily forms spherical inclusions desi...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Yuki Kawaguchi, Masato Taoka, Takahiro Takekiyo, Takamasa Uekita, Ikuo Shoji, Naomi Hachiya, Tohru Ichimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Online Access:http://europepmc.org/articles/PMC5215751?pdf=render