Goistrat: gene-of-interest-based sample stratification for the evaluation of functional differences

Abstract Purpose Understanding the impact of gene expression in pathological processes, such as carcinogenesis, is crucial for understanding the biology of cancer and advancing personalised medicine. Yet, current methods lack biologically-informed-omics approaches to stratify cancer patients effecti...

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Bibliographic Details

Published in:	BMC Bioinformatics
Main Authors:	Carlos Uziel Pérez Malla, Jessica Kalla, Andreas Tiefenbacher, Gabriel Wasinger, Kilian Kluge, Gerda Egger, Raheleh Sheibani-Tezerji
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Subjects:	Gene of interest GSVA GSEA Node2Vec FOLH1 PSMA
Online Access:	https://doi.org/10.1186/s12859-025-06109-0