Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains

Antigen recognition by mammalian antibodies represents the most diverse setting for protein-protein interactions, because antibody variable regions contain exceptionally diverse variable gene repertoires of DNA sequences containing combinatorial, non-templated junctional mutational diversity. Some a...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Jinhui Dong, Jessica A. Finn, Peter A. Larsen, Timothy P. L. Smith, James E. Crowe
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-03-01
Subjects:	lymphocytes monoclonal antibody antigen-antibody recognition Bos taurus ultralong CDRH3 crystal structure
Online Access:	https://www.frontiersin.org/article/10.3389/fimmu.2019.00558/full