The recent advancement of TCR-T cell therapies for cancer treatment

Adoptive cell therapies involve infusing engineered immune cells into cancer patients to recognize and eliminate tumor cells. Adoptive cell therapy, as a form of living drug, has undergone explosive growth over the past decade. The recognition of tumor antigens by the T-cell receptor (TCR) is one of...

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Bibliographic Details
Published in:Acta Biochimica et Biophysica Sinica
Main Authors: Zhao Xiang, Shao Shuai, Hu Lanxin
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-04-01
Subjects:
TCR
pMHC
TCR-T cell therapy
tumor antigen
catch bond
dynamic binding
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024034

Internet

https://www.sciengine.com/doi/10.3724/abbs.2024034

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