Parathyroid hormone (1–34) retards the lumbar facet joint degeneration and activates Wnt/β-catenin signaling pathway in ovariectomized rats

Abstract Purpose Facet joint degeneration (FJD) is a major cause of low back pain. Parathyroid hormone (PTH) (1–34) is commonly used to treat osteoporosis. However, little is known about its effects on FJD induced by estrogen deficiency. This study aims to investigate the effects of PTH (1–34) on FJ...

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Bibliographic Details
Published in:Journal of Orthopaedic Surgery and Research
Main Authors: Yu Gou, Hetong Li, Xun Sun, Desheng Chen, Faming Tian
Format: Article
Language:English
Published: BMC 2024-06-01
Subjects:
Joint degeneration
Lumbar facet joint
Parathyroid hormone
Wnt/β-catenin signaling
Cartilage
Subchondral bone
Online Access:https://doi.org/10.1186/s13018-024-04817-6

Internet

https://doi.org/10.1186/s13018-024-04817-6

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