Gadolinium Oxide Nanoparticles Induce Toxicity in Human Endothelial HUVECs via Lipid Peroxidation, Mitochondrial Dysfunction and Autophagy Modulation

In spite of the potential preclinical advantage of Gd₂O₃ nanoparticles (designated here as GO NPs) over gadolinium-based compounds in MRI, recent concerns of gadolinium deposits in various tissues undergoing MRI demands a mechanistic investigation. Hence...

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Bibliographic Details

Published in:	Nanomaterials
Main Authors:	Mohd Javed Akhtar, Maqusood Ahamed, Hisham Alhadlaq
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Subjects:	oxidative stress ROS autophagy lysosome necrosis
Online Access:	https://www.mdpi.com/2079-4991/10/9/1675