Spatiotemporal orchestration of macrophage activation trajectories by Vγ4 T cells during skin wound healing

Summary: Dysregulated macrophage polarization from pro-inflammatory M1 to anti-inflammatory M2 phenotypes underlies impaired cutaneous wound healing. This study reveals Vγ4+ γδ T cells spatiotemporally calibrate macrophage trajectories during skin repair via sophisticated interferon-γ (IFN-γ) condit...

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Bibliographic Details

Published in:	iScience
Main Authors:	Wengang Hu, Xiaorong Zhang, Zhongyang Liu, Jiacai Yang, Hao Sheng, Zhihui Liu, Cheng Chen, Ruoyu Shang, Yunxia Chen, Yifei Lu, Xiaohong Hu, Yong Huang, Wenjing Yin, Xin Cai, Dejiang Fan, Lingfeng Yan, Jianlei Hao, Gaoxing Luo, Weifeng He
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Subjects:	Biological sciences Immune response Components of the immune system
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224007673