Tolerance and heteroresistance to echinocandins in Candida auris: conceptual issues, clinical implications, and outstanding questions

ABSTRACT Candida auris is a significant public health threat due to its environmental persistence and multidrug resistance, with echinocandins being the preferred treatment. However, in addition to resistance, echinocandin tolerance and heteroresistance may contribute to treatment challenges. Echino...

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Bibliographic Details

Published in:	mSphere
Main Authors:	Erika Shor, David S. Perlin, Dimitrios P. Kontoyiannis
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-05-01
Subjects:	Candida auris echinocandins heteroresistance tolerance
Online Access:	https://journals.asm.org/doi/10.1128/msphere.00161-25