Kaposi's sarcoma herpesvirus latency-associated nuclear antigen broadly regulates viral gene expression and is essential for lytic infection.

Kaposi's sarcoma herpesvirus (KSHV) is a leading cause of malignancy in AIDS and current therapies are limited. Like all herpesviruses, KSHV infection can be latent or lytic. KSHV latency-associated nuclear antigen (LANA) is essential for viral genome persistence during latent infection. LANA a...

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Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Shijun Li, Mengbo Wang, Nicholas Van Sciver, Agnieszka Szymula, Vinayak Sadasivam Tumuluri, Athira George, Akshaya Ramachandran, Komal Raina, Catarina N Costa, Bo Zhao, Majid Kazemian, J Pedro Simas, Kenneth M Kaye
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2024-01-01
Online Access:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011907&type=printable