The Endothelial Tyrosine Phosphatase SHP-1 Plays an Important Role for Vascular Haemostasis in TNFα-Induced Inflammation In Vivo

Introduction. Inflammation and endothelium-derived superoxides are important pathomechanisms in atherothrombotic diseases. We could previously show that the tyrosine phosphatase SHP-1 acts as a negative regulator in endothelial superoxide production. In this study we investigated the influence of SH...

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Bibliographic Details
Published in:Mediators of Inflammation
Main Authors: Elisabeth Koch, Joachim Pircher, Thomas Czermak, Erik Gaitzsch, Stefan Alig, Hanna Mannell, Markus Niemeyer, Florian Krötz, Markus Wörnle
Format: Article
Language:English
Published: Wiley 2013-01-01
Online Access:http://dx.doi.org/10.1155/2013/279781