Determination of CSF GFAP, CCN5, and vWF Levels Enhances the Diagnostic Accuracy of Clinically Defined MS From Non-MS Patients With CSF Oligoclonal Bands

BackgroundInclusion of cerebrospinal fluid (CSF) oligoclonal IgG bands (OCGB) in the revised McDonald criteria increases the sensitivity of diagnosis when dissemination in time (DIT) cannot be proven. While OCGB negative patients are unlikely to develop clinically definite (CD) MS, OCGB positivity m...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Fay Probert, Tianrong Yeo, Yifan Zhou, Megan Sealey, Siddharth Arora, Jacqueline Palace, Timothy D. W. Claridge, Rainer Hillenbrand, Johanna Oechtering, Jens Kuhle, David Leppert, Daniel C. Anthony
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-02-01
Subjects:	diagnosis metabolomics (OMICS) multiple sclerosis (MS) proteomics oligoclonal band
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.811351/full