Perivascular Stromal Cells Instruct Glioblastoma Invasion, Proliferation, and Therapeutic Response within an Engineered Brain Perivascular Niche Model

Abstract Glioblastoma (GBM) tumor cells are found in the perivascular niche microenvironment and are believed to associate closely with the brain microvasculature. However, it is largely unknown how the resident cells of the perivascular niche, such as endothelial cells, pericytes, and astrocytes, i...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Mai T. Ngo, Jann N. Sarkaria, Brendan A.C. Harley
Format:	Article
Language:	English
Published:	Wiley 2022-11-01
Subjects:	angiocrine glioblastoma hydrogel invasion tumor vascular
Online Access:	https://doi.org/10.1002/advs.202201888