Detection of fibrotic remodeling of epicardial adipose tissue in patients with atrial fibrillation: Imaging approach based on histological observation

Background: Fibrotic remodeling of epicardial adipose tissue (EAT) is crucial for proinflammatory atrial myocardial fibrosis, which leads to atrial fibrillation (AF). Objectives: We tested the hypothesis that the ratio of central to marginal adipocyte diameter in EAT represents its fibrotic remodeli...

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Bibliographic Details

Published in:	Heart Rhythm O2
Main Authors:	Yumi Ishii, MD, Ichitaro Abe, MD, PhD, Shintaro Kira, MD, PhD, Taisuke Harada, MD, Masayuki Takano, MD, Takahiro Oniki, MD, PhD, Hidekazu Kondo, MD, PhD, Yasushi Teshima, MD, PhD, Kunio Yufu, MD, PhD, Takashi Shuto, MD, PhD, Tomoyuki Wada, MD, PhD, Mikiko Nakagawa, MD, PhD, Tatsuo Shimada, PhD, Yoshiki Asayama, MD, PhD, Shinji Miyamoto, MD, PhD, Naohiko Takahashi, MD, PhD
Format:	Article
Language:	English
Published:	Elsevier 2021-08-01
Subjects:	Atrial fibrillation Computed tomography Epicardial adipose tissue Fat attenuation Fibrosis Inflammation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666501821000891