Interplay between oncolytic measles virus, macrophages and cancer cells induces a proinflammatory tumor microenvironment

Attenuated measles virus (MV) exerts its oncolytic activity in malignant pleural mesothelioma (MPM) cells that lack type-I interferon (IFN-I) production or responsiveness. However, other cells in the tumor microenvironment (TME), such as myeloid cells, possess functional antiviral pathways. In this...

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出版年:	OncoImmunology
主要な著者:	Camille Chatelain, Laurine Berland, Marion Grard, Nicolas Jouand, Judith Fresquet, Joëlle Nader, Ugo Hirigoyen, Tacien Petithomme, Chantal Combredet, Elvire Pons-Tostivint, Delphine Fradin, Lucas Treps, Christophe Blanquart, Nicolas Boisgerault, Frédéric Tangy, Jean-François Fonteneau
フォーマット:	論文
言語:	英語
出版事項:	Taylor & Francis Group 2024-12-01
主題:	Measles virus mesothelioma oncolytic immunotherapy tumor associated macrophages type I interferon
オンライン･アクセス:	https://www.tandfonline.com/doi/10.1080/2162402X.2024.2377830