The tumor biological significance of RNF43 and LRP1B in gastric cancer is complex and context-dependent

Abstract Gastric cancer (GC) is the fifth most common cancer in the world with a poor prognosis. Both RNF43 and LRP1B function as tumor suppressors in the Wnt signaling pathway and have been described to be frequently mutated in GC. In this study of a large and well characterized cohort of 446 GCs w...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Scientific Reports
المؤلفون الرئيسيون: Bente Holm, Stephan Barsuhn, Hans-Michael Behrens, Sandra Krüger, Christoph Röcken
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Portfolio 2023-02-01
الوصول للمادة أونلاين:https://doi.org/10.1038/s41598-023-30294-8