Transcriptomic profiling of blood from autoimmune hepatitis patients reveals potential mechanisms with implications for management.

Autoimmune hepatitis (AIH) is a poorly understood, chronic disease, for which corticosteroids are still the mainstay of therapy and most patients undergo liver biopsy to obtain a diagnosis. We aimed to determine if there was a transcriptomic signature of AIH in the peripheral blood and investigate u...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Michele May-Sien Tana, Arielle Klepper, Amy Lyden, Angela Oliveira Pisco, Maira Phelps, Breann McGee, Kelsey Green, Sandy Feng, Joseph DeRisi, Emily Dawn Crawford, Craig S Lammert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0264307&type=printable