Lassa virus activates myeloid dendritic cells but suppresses their ability to stimulate T cells.

Lassa virus (LASV) is responsible for a viral hemorrhagic fever in humans and the death of 3,000 to 5,000 people every year. The immune response to LASV is poorly understood, but type I interferon (IFN-I) and T-cell responses appear to be critical for the host. We studied the response of myeloid den...

Full description

Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Justine Schaeffer, Xavier Carnec, Stéphanie Reynard, Mathieu Mateo, Caroline Picard, Natalia Pietrosemoli, Marie-Agnès Dillies, Sylvain Baize
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2018-11-01
Online Access:	http://europepmc.org/articles/PMC6258464?pdf=render