Divalent Metal Uptake and the Role of ZIP8 in Host Defense Against Pathogens

Manganese (Mn) and Zinc (Zn) are essential micronutrients whose concentration and location within cells are tightly regulated at the onset of infection. Two families of Zn transporters (ZIPs and ZnTs) are largely responsible for regulation of cytosolic Zn levels and to a certain extent, Mn levels, a...

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Bibliographic Details
Published in:Frontiers in Cell and Developmental Biology
Main Authors: Derrick R. Samuelson, Sabah Haq, Daren L. Knoell
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.924820/full