Galectin-receptor interaction: a key player in liver fibrosis induced by Schistosoma japonicum infection

Abstract Background Schistosoma japonicum eggs lodge in the liver and induce a fibrotic granulomatous immune response in the liver of host. Galectin 3 (Gal-3) is a protein implicated in fibrosis in multiple organs. However, the pathology and molecular mechanisms promoting hepatic granuloma formation...

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Bibliographic Details

Published in:	Parasites & Vectors
Main Authors:	Ziyun Huang, Xingzhuo Liu, Shiguang Huang, Fangli Lu
Format:	Article
Language:	English
Published:	BMC 2024-05-01
Subjects:	Schistosoma japonicum Galectin-receptor interactions Liver fibrosis Macrophage autophagy Mice
Online Access:	https://doi.org/10.1186/s13071-024-06314-5