Avoidance of recognition sites of restriction-modification systems is a widespread but not universal anti-restriction strategy of prokaryotic viruses

Abstract Background Restriction-modification (R-M) systems protect bacteria and archaea from attacks by bacteriophages and archaeal viruses. An R-M system specifically recognizes short sites in foreign DNA and cleaves it, while such sites in the host DNA are protected by methylation. Prokaryotic vir...

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Bibliographic Details

Published in:	BMC Genomics
Main Authors:	I. S. Rusinov, A. S. Ershova, A. S. Karyagina, S. A. Spirin, A. V. Alexeevski
Format:	Article
Language:	English
Published:	BMC 2018-12-01
Subjects:	Restriction-modification systems Anti-restriction Site avoidance Compositional bias Bacteriophages Archaeal viruses
Online Access:	http://link.springer.com/article/10.1186/s12864-018-5324-3