Picornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus

The compartmentalization of DNA replication and gene transcription in the nucleus and protein production in the cytoplasm is a defining feature of eukaryotic cells. The nucleus functions to maintain the integrity of the nuclear genome of the cell and to control gene expression based on intracellular...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Dylan eFlather, Bert L Semler
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-06-01
Subjects:	Cardiovirus Enterovirus nucleus IRES picornavirus Nucleocytoplasmic trafficking
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00594/full