Revealing polygenic pleiotropy using genetic risk scores for asthma

Summary: In this study we examined how genetic risk for asthma associates with different features of the disease and with other medical conditions and traits. Using summary statistics from two multi-ancestry genome-wide association studies of asthma, we modeled polygenic risk scores (PRSs) and valid...

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Bibliographic Details
Published in:HGG Advances
Main Authors: Matthew Dapas, Yu Lin Lee, William Wentworth-Sheilds, Hae Kyung Im, Carole Ober, Nathan Schoettler
Format: Article
Language:English
Published: Elsevier 2023-10-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247723000659