ASFV pE146L-induced ER remodeling is essential for viral replication

ABSTRACT African swine fever virus (ASFV) causes a severe hemorrhagic disease, posing a significant threat to the global pig industry. Although the ASFV encodes nearly 200 proteins, the functions of many remain unknown. Here, we identify the inner envelope protein pE146L as essential for ASFV replic...

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Bibliographic Details

Published in:	Journal of Virology
Main Authors:	Yilin Guo, Sai Niu, Xueying Wang, Zixuan Wang, Rui Liang, Yubei Tan, Zhen Fu, Zhelin Su, Juan Xu, Hongjun Chen, Yuejun Shi, Limeng Sun, Guiqing Peng
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-09-01
Subjects:	African swine fever virus E146L protein ER remodeling virus assembly
Online Access:	https://journals.asm.org/doi/10.1128/jvi.00834-25