Research of neuroprotective properties of TrkA-receptor agonist GK-2 on model of oxidative stress in human vascular endothelial cells (HUVEC)

Oxidative stress resulted to decrease in cells viability compared to the control (78 ± 5 % and 100 ± 6 %, respectively, р < 0,05). GK-2 and NGF prevented H2O2-induced HUVEC cells damages (95 ± 3 % for HA-2 and 97 ± 4 % for NGF vs. 78 ± 5 % for H2O2, p < 0.05). In control the number of cells wi...

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Bibliographic Details

Published in:	Фармакокинетика и Фармакодинамика
Main Authors:	T. A. Antipova, S. V. Nikolaev, S. A. Kryzhanovsky, E. S. Pekeldina
Format:	Article
Language:	Russian
Published:	LLC “Publisher OKI” 2019-01-01
Subjects:	ngf димерный дипептидный миметик гк-2 huvec клетки эндотелия человека окислительный стресс апоптоз dimeric dipeptide mimetic gk-2 huvec oxidative stress apoptosis
Online Access:	https://www.pharmacokinetica.ru/jour/article/view/82