Estimating directional epistasis
Epistasis, i.e. the fact that gene effects depend on the genetic background, is a direct consequence of the complexity of genetic architectures. Despite this, most of the models used in evolutionary and quantitative genetics pay scant attention to genetic interactions. For instance, the traditional...
| Published in: | Frontiers in Genetics |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-07-01
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00198/full |