Loss of ZNF148 enhances insulin secretion in human pancreatic β cells

Insulin secretion from pancreatic β cells is essential to the maintenance of glucose homeostasis. Defects in this process result in diabetes. Identifying genetic regulators that impair insulin secretion is crucial for the identification of novel therapeutic targets. Here, we show that reduction of Z...

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書誌詳細

出版年:	JCI Insight
主要な著者:	Eleonora de Klerk, Yini Xiao, Christopher H. Emfinger, Mark P. Keller, David I. Berrios, Valentina Loconte, Axel A. Ekman, Kate L. White, Rebecca L. Cardone, Richard G. Kibbey, Alan D. Attie, Matthias Hebrok
フォーマット:	論文
言語:	英語
出版事項:	American Society for Clinical investigation 2023-06-01
主題:	Metabolism Stem cells
オンライン･アクセス:	https://doi.org/10.1172/jci.insight.157572