Ameliorative effects of Fingolimod (FTY720) on microglial activation and psychosis-related behavior in short term cuprizone exposed mice

Abstract Schizophrenia is a psychiatric disorder that affects around 1% of the population in widespread populations, with severe cases leading to long-term hospitalization and necessitation of lifelong treatment. Recent studies on schizophrenia have highlighted the involvement of inflammatory and im...

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Bibliographic Details
Published in:Molecular Brain
Main Authors: Siyao Li, Koki Sakurai, Masahiro Ohgidani, Takahiro A. Kato, Takatoshi Hikida
Format: Article
Language:English
Published: BMC 2023-07-01
Subjects:
Short-term cuprizone exposure
Psychosis
Fingolimod
Microglial activation
Neuroinflammation
Online Access:https://doi.org/10.1186/s13041-023-01047-5

Internet

https://doi.org/10.1186/s13041-023-01047-5

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