Quality of extracellular vesicle images by transmission electron microscopy is operator and protocol dependent

Transmission electron microscopy (TEM) has nanometre resolution and can be used to distinguish single extracellular vesicles (EVs) from non-EV particles. TEM images of EVs are a result of operator image selection. To which extent operator image selection reflects the overall sample quality, and to w...

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Bibliographic Details

Published in:	Journal of Extracellular Vesicles
Main Authors:	L. G. Rikkert, R. Nieuwland, L. W. M. M. Terstappen, F. A. W. Coumans
Format:	Article
Language:	English
Published:	Wiley 2019-12-01
Subjects:	exosomes extracellular vesicles (evs) microvesicles negative staining transmission electron microscopy (tem) urine
Online Access:	http://dx.doi.org/10.1080/20013078.2018.1555419