The influence of immune checkpoint blockade on the outcomes of allogeneic hematopoietic stem cell transplantation

The principle of immune checkpoint blockade therapy is based on the activation of T cells. Immune checkpoint inhibitors (ICIs), such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, have demonstrated effectiveness in treating solid tumors by reinvigorating the immune system to recognize and eliminate...

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書誌詳細

出版年:	Frontiers in Immunology
主要な著者:	Yalei Hu, Yuxin Wang, Kaili Min, Huisheng Zhou, Xiaoning Gao
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2024-11-01
主題:	immune checkpoint inhibitors programmed cell death protein 1 programmed cell death 1 ligand 1 allogeneic hematopoietic cell transplant graft-versus-host disease immune-related adverse events
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1491330/full