Leptin Signaling in the Hypothalamus: Cellular Insights and Therapeutic Perspectives in Obesity

Leptin, an adipocyte-derived hormone, plays a central role in the regulation of energy homeostasis by acting on distinct hypothalamic nuclei. This review explores recent advances in our understanding of leptin’s region-specific actions within the arcuate nucleus, ventromedial hypothalamus, dorsomedi...

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Bibliographic Details
Published in:Endocrines
Main Author: Milen Hristov
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Subjects:
Online Access:https://www.mdpi.com/2673-396X/6/3/42