Gut sensory neurons as regulators of neuro-immune-microbial interactions: from molecular mechanisms to precision therapy for IBD/IBS

Abstract As potentially important biosensors within the intestinal mucosal barrier, gut sensory neurons appear to dynamically orchestrate tissue homeostasis through multimodal integration of mechanical forces, chemical cues, and microbial metabolites. While current research indicates gut sensory neu...

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Bibliographic Details

Published in:	Journal of Neuroinflammation
Main Authors:	Ning Sun, Li-Shuang Cao, Wan-Yu Xia, Jun-Meng Wang, Qiao-Feng Wu
Format:	Article
Language:	English
Published:	BMC 2025-07-01
Subjects:	Inflammatory bowel disease (IBD) Irritable bowel syndrome (IBS) Sensory neurons Neuro-immunology Microorganism
Online Access:	https://doi.org/10.1186/s12974-025-03500-9