Synthesis of Two Novel Azilsartan Cocrystals: Preparation, Physicochemical Characterization and Solubility Studies

Azilsartan is a novel angiotension II receptor blocker primarily used to treat high blood pressure. This is not a formulation-friendly molecule largely due to the inherent water-solubility pitfalls. In this paper, two novel cocrystals of azilsartan (AZ) were studied (AZ-BIP, AZ-BPE; BIP = 4,4′-bipyr...

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Bibliographic Details

Published in:	Crystals
Main Authors:	Lei Gao, Xian-Rui Zhang
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Subjects:	azilsartan 4,4′-bipyridine cocrystal solubility structure X-ray diffraction
Online Access:	https://www.mdpi.com/2073-4352/10/9/739