Evaluating cancer etiology and risk with a mathematical model of tumor evolution

Modelling how endogenous mutations accumulate in tissues is valuable to understand how cancers develop and evolve. Here, the authors establish a mathematical model that can predict the number of endogenous somatic mutations in the lifetime of tissues and approximate the time to cancer development.

Bibliographic Details
Published in:Nature Communications
Main Authors: Sophie Pénisson, Amaury Lambert, Cristian Tomasetti
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Online Access:https://doi.org/10.1038/s41467-022-34760-1