Imipramine Treatment Alters Sphingomyelin, Cholesterol, and Glycerophospholipid Metabolism in Isolated Macrophage Lysosomes

Lysosomes are degradative organelles that facilitate the removal and recycling of potentially cytotoxic materials and mediate a variety of other cellular processes, such as nutrient sensing, intracellular signaling, and lipid metabolism. Due to these central roles, lysosome dysfunction can lead to d...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Jacob M. Albright, Matthew J. Sydor, Jonathan Shannahan, Christina R. Ferreira, Andrij Holian
Format:	Article
Language:	English
Published:	MDPI AG 2023-12-01
Subjects:	lipids lipidomics sphingolipids ceramide phosphatidylcholine lysophosphatidylcholine
Online Access:	https://www.mdpi.com/2218-273X/13/12/1732