Predicting anticancer drug sensitivity on distributed data sources using federated deep learning

Drug sensitivity prediction plays a crucial role in precision cancer therapy. Collaboration among medical institutions can lead to better performance in drug sensitivity prediction. However, patient privacy and data protection regulation remain a severe impediment to centralized prediction studies....

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Xiaolu Xu, Zitong Qi, Xiumei Han, Aiguo Xu, Zhaohong Geng, Xinyu He, Yonggong Ren, Zhaojun Duo
Format:	Article
Language:	English
Published:	Elsevier 2023-08-01
Subjects:	Federated learning Deep learning Multi-class focal loss Drug sensitivity prediction Gene expression
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023058231