Regulating SLC7A11/GSH/GPX4 axis by glucose dyshomeostasis to simultaneously promote disulfidptosis, cuproptosis and ferroptosis

As one of the key targets of tumor metabolic therapy, glucose dyshomeostasis by disrupting glucose metabolism possesses the potential to reverse therapeutic resistance of a variety of regulated cell deaths (RCDs), but the functional pathways are not fully revealed and employed. Herein, we demonstrat...

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Bibliographic Details

Published in:	Bioactive Materials
Main Authors:	Mengsi Zhang, Hao Zheng, Hao Jin, Xuanqi Zhu, Shuwei Liu, Yang Chen, Hao Zhang, Songling Zhang
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2025-12-01
Subjects:	Ferroptosis Cuproptosis Disulfidptosis SLC7A11/GSH/GPX4 axis Glucose metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452199X25004086