Resistance against two lytic phage variants attenuates virulence and antibiotic resistance in Pseudomonas aeruginosa

BackgroundBacteriophage therapy is becoming part of mainstream Western medicine since antibiotics of clinical use tend to fail. It involves applying lytic bacteriophages that self-replicate and induce cell lysis, thus killing their hosts. Nevertheless, bacterial killing promotes the selection of res...

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發表在:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Juan Carlos García-Cruz, Xareni Rebollar-Juarez, Aldo Limones-Martinez, Cristian Sadalis Santos-Lopez, Shotaro Toya, Toshinari Maeda, Corina Diana Ceapă, Lucia Blasco, María Tomás, Clara Estela Díaz-Velásquez, Felipe Vaca-Paniagua, Miguel Díaz-Guerrero, Daniel Cazares, Adrián Cazares, Melisa Hernández-Durán, Luis Esaú López-Jácome, Rafael Franco-Cendejas, Fohad Mabood Husain, Altaf Khan, Mohammed Arshad, Rosario Morales-Espinosa, Ana María Fernández-Presas, Frederic Cadet, Thomas K. Wood, Rodolfo García-Contreras
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2024-01-01
主題:	virulence tradeoffs biofilm phage resistance phage therapy
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1280265/full