Pilot PET study of vaginally administered bioadhesive nanoparticles in cynomolgus monkeys: Kinetics and safety evaluation

Abstract Long‐lasting vaginal dosage forms could improve the therapeutic efficacy of vaginal microbicides, but achieving long‐term delivery to the vaginal canal has been a significant challenge. To advance understanding of vaginal dosage retention and biodistribution, we describe a method of noninva...

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Bibliographic Details

Published in:	Bioengineering & Translational Medicine
Main Authors:	Molly K. Grun, Praveen Honhar, Yazhe Wang, Samantha Rossano, Minsoo Khang, Hee Won Suh, Krista Fowles, Harvey J. Kliman, Alessandra Cavaliere, Richard E. Carson, Bernadette Marquez‐Nostra, W. Mark Saltzman
Format:	Article
Language:	English
Published:	Wiley 2024-09-01
Subjects:	biocompatible biodegradable microbicide nanoparticle vaginal drug delivery
Online Access:	https://doi.org/10.1002/btm2.10661