Activation of non-classical Wnt signaling pathway effectively enhances HLA-A presentation in acute myeloid leukemia

ObjectiveThe escape from T cell-mediated immune surveillance is an important cause of death for patients with acute myeloid leukemia (AML). This study aims to identify clonal heterogeneity in leukemia progenitor cells and explore molecular or signaling pathways associated with AML immune escape.Meth...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	YuHan Ma, JunShuai Yue, Ling Gao, JingXin Zhou, Wei Chen, Jing Su, JinRong Yao, QiaoMei Shi, XiaoDong Zhao, Na Hu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-06-01
Subjects:	acute myeloid leukemia HLA-A immune escape non-classical Wnt signaling pathway scRNA-seq
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1336106/full