Metabolic differences in MSTN and FGF5 dual-gene edited sheep muscle cells during myogenesis

Abstract Dynamic metabolic reprogramming occurs at different stages of myogenesis and contributes to the fate determination of skeletal muscle satellite cells (MuSCs). Accumulating evidence suggests that mutations in myostatin (MSTN) have a vital role in regulating muscle energy metabolism. Here, we...

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Bibliographic Details

Published in:	BMC Genomics
Main Authors:	Mingming Chen, Yan Li, Xueling Xu, Shuqi Wang, Zhimei Liu, Shiyu Qi, Dandan Si, Zhuo Man, Shoulong Deng, Guoshi Liu, Yue Zhao, Kun Yu, Zhengxing Lian
Format:	Article
Language:	English
Published:	BMC 2024-06-01
Subjects:	MSTN FGF5 Sheep Skeketal muscle cells Metabolomics
Online Access:	https://doi.org/10.1186/s12864-024-10494-w