ATR addiction in multiple myeloma: synthetic lethal approaches exploiting established therapies

Therapeutic strategies designed to tinker with cancer cell DNA damage response have led to the widespread use of PARP inhibitors for BRCA1/2-mutated cancers. In the haematological cancer multiple myeloma, we sought to identify analogous synthetic lethality mechanisms that could be leveraged upon es...

詳細記述

書誌詳細
出版年:Haematologica
主要な著者: Oronza A. Botrugno, Silvia Bianchessi, Desirée Zambroni, Michela Frenquelli, Daniela Belloni, Lucia Bongiovanni, Stefania Girlanda, Simona Di Terlizzi, Marina Ferrarini, Elisabetta Ferrero, Maurilio Ponzoni, Magda Marcatti, Giovanni Tonon
フォーマット: 論文
言語:英語
出版事項: Ferrata Storti Foundation 2019-11-01
オンライン・アクセス:https://haematologica.org/article/view/9563