Loss of phosphatase activity in PTEN (phosphatase and tensin homolog deleted on chromosome ten) results in endometrial carcinoma in humans: An in-silico study

The tumour suppressor gene, PTEN (Phosphatase and Tensin homolog deleted on chromosome Ten), can act as both protein phosphatase and lipid phosphatase, is known to play a vital role in Pi3k signalling pathway. In humans, it is located at 10q23. Loss of its phosphatase and catalytic activity is assoc...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Sunil Kanti Mondal, Madhab Kumar Sen
Format:	Article
Language:	English
Published:	Elsevier 2020-01-01
Subjects:	Systems biology Bioinformatics Biotechnology Molecular biology Tumour suppressor gene PTEN
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844019367659